The lunacy of once a week dosing of Vitamin D. I have spoken for years of following the “Ancient Wisdom” as it relates to health.

Why the medical world insists that it can improve on nature astounds me at times and this is the perfect example. Who would eat once a week and expect it to produce health! This new study comparing the yo-yo effect of once a week Vitamin D to every day dosing indicates clearly the path we should be following.

New concepts about the way the body utilizes vitamin D in autocrine/paracrine functions, in addition to the well-established endocrine functions, have shed light on the importance of obtaining a daily dose of vitamin D3, versus doses at… Click To Tweet

New concepts about the way the body utilizes vitamin D in autocrine/paracrine functions, in addition to the well-established endocrine functions, have shed light on the importance of obtaining a daily dose of vitamin D3, versus doses at weekly, monthly, or longer intervals. Vitamin D3 is a relatively short-lived compound in the body with a half-life of less than 24 hours, making serum D3 an unreliable marker for an individual’s vitamin D status. The short half-life also means that dosing intervals of a week or greater can lead to depletion of vitamin D3 in the serum altogether.

The chart below illustrates the effect of two different dosing intervals on the amount of vitamin D3 in the blood. Daily dosing results in a fairly steady level of serum D3 with little fluctuation and risk for depletion, whereas weekly dosing (taking a single dose at 7 times the daily dose, once per week) causes a spike in vitamin D3 level, which then quickly drops and leaves the blood vitamin D3 depleted.

Because certain physiological processes depend on the availability of vitamin D3 in the blood, dosing at intervals that allow for its depletion can lead to negative consequences. For more detailed information, refer to the Vitamin D Dosing Interval video by Dr. Bruce Hollis.